Steps on how to take a screenshot on Windows 11 of a specific portion:

1. Press Windows + Shift + S. This opens the Snipping Tool overlay.
2. Your screen will dim, and a toolbar will appear at the top.
3. Use your mouse to select the portion of the screen you want to capture.
4. The screenshot is automatically copied to the clipboard and you can copy paste or save the Screenshot.

Clearing Cache can fix the issue of mouse cursor disappears follow the given steps:
Press the Windows key and type Disk Cleanup in the search field.
Open the program Select the type of files you want to clean from your PC and select the option “Clean up system files.”
Wait for the process to complete and check if the cursor appears on the screen.

Source: Datarecove.com